Chemistry

Institute of Biomedical Engineering

Leah Cowen

Sinai Health

Sunnybrook Health Sciences Centre

Temerty Faculty of Medicine

Unity Health

Cell and Systems Biology

Anthropology

Astronomy & Astrophysics

Biochemistry

Centre for Addiction and Mental Health

Dalla Lana School of Public Health

Computer Science

Ecology and Evolutionary Biology

Hospital for Sick Children

Laboratory Medicine and Pathobiology

Leslie Dan Faculty of Pharmacy

Mathematics

Physics

Psychology

University Health Network

UTIAS

Subheadline

From better batteries to preventing memory loss, nearly four dozen projects at U of T and its partner hospitals are being supported by the Ontario Research Fund

Researchers in the �ؿ�ζSM’s Thermal Management Systems (TMS) Laboratory are working to improve the way battery systems handle heat and develop structural battery pack components. 

“Whether they are being used for electric vehicles or for stationary energy storage systems that reduce strain on the grid, lithium-ion batteries are transforming the way we use electricity,” said Carlos Da Silva, senior research associate at the TMS Lab in the Faculty of Applied Science & Engineering and executive director of U of T’s Electrification Hub.

“Unfortunately, today’s batteries are still sensitive to temperature: if they get too cold or too hot, it can degrade their performance and even present safety risks. We are working on new technologies that make batteries more resilient to thermal fluctuations.”

The battery-related research is among nearly four dozen projects at U of T and its partner hospitals that are receiving almost $35 million in support through the Ontario Research Fund – Research Excellence (ORF-RE) and the Ontario Research Fund – Small Infrastructure (ORF-SIF). (See the full list of projects and their principal researchers below).

"Research at the �ؿ�ζSM and at all universities and colleges across Ontario is the foundation of the province’s competitiveness now and in the future,” said Leah Cowen, U of T’s vice-president, research and innovation, and strategic initiatives.

“This investment protects and advances cutting-edge, made-in-Ontario research in important economic sectors and helps ensure universities can continue to train, attract and retain the world’s top talent."

At U of T Engineering’s TMS Lab, researchers led by Cristina Amon, a University Professor in the department of mechanical and industrial engineering, are working on two funded projects. They are developing advanced computational modelling and digital twin methodologies that predict and optimize how heat flows through battery packs. The methodologies are carefully calibrated and validated through industry-relevant experiments in the lab.

Senior Research Associate Carlos Da Silva, left, and University Professor Cristina Amon, right, chat in the Faculty of Applied Science & Engineering's Thermal Management Systems Laboratory (photo by Aaron Demeter)

These methodologies will help battery designers anticipate and prevent thermal management challenges before they arise. It can also enable them to optimize the design and deployment of fire mitigation measures, such as ultra-thin heat barriers, within their battery systems.

The team is also collaborating with Ford Canada and several other companies in the energy storage space. For example, they have worked with Jule (powered by eCAMION) on the development of direct current electric vehicle fast chargers with integrated battery energy storage systems, one of which was recently unveiled on the U of T campus.

“We are grateful for this ORF-RE funding, which will accelerate our research and help us further expand our partnerships, ensuring that battery thermal innovations have a seamless transition from the lab to the marketplace,” Amon said.

“As a result of this work, the next generation of batteries will be safer and more resilient than ever before, which is especially important in colder climates like ours here in Ontario.” 

Ontario Research Fund – Research Excellence:

Cristina Amon in the department of mechanical & industrial engineering in the Faculty of Applied Science & Engineering – Powering Ontario’s grid transformation and electric vehicle fast charging with thermally resilient battery energy storage & Next-gen electric vehicle battery systems: Lightweight, thermally performant and fire safe for all climates
Morgan Barense in the department of psychology in the Faculty of Arts & Science – HippoCamera: Digital memory rehabilitation to combat memory loss
Aimy Bazylak in the department of mechanical & industrial engineering in the Faculty of Applied Science and Engineering – RECYCLEAN: Critical minerals recycling & re-manufacturing for the energy transition
Ian Connell at University Health Network and the department of medical biophysics in the Temerty Faculty of Medicine – MRI-compatible innovations for neuromodulation
Simon Graham at Sunnybrook Health Sciences Centre and the department of medical biophysics in the Temerty Faculty of Medicine – Technological innovations for clinical MRI of the brain at 7 tesla
Clinton Groth in the Institute for Aerospace Studies in the Faculty of Applied Science & Engineering – Hydrogen as a sustainable aviation fuel – combustion research to remove impediments to adoption in gas turbine engines
James Kennedy at Centre for Addiction and Mental Health and the department of psychiatry in the Temerty Faculty of Medicine – Clinical utility and enhancements of a pharmacogenomic decision support tool for mental health patients
Shaf Keshavjee at University Health Network and the department of surgery in the Temerty Faculty of Medicine – Advanced solutions to human lung preservation and assessment using artificial intelligence
Aviad Levis in the department of computer science in the Faculty of Arts & Science – AI and quantum enhanced astronomy
JoAnne McLaurin at Sunnybrook Health Sciences Centre and the department of laboratory medicine & pathobiology in the Temerty Faculty of Medicine – Conversion of astrocytes to neurons to treat neurodegenerative diseases of the brain and the eye
R. J. Dwayne Miller in the department of chemistry in the Faculty of Arts & Science – PicoSecond InfraRed Laser (PIRL) “cancer knife” with complete biodiagnostics via spatial imaging mass spectrometry
Javad Mostaghimi in the department of mechanical & industrial engineering in the Faculty of Applied Science & Engineering – A new generation of compact, transportable mass spectrometers for rapid, in-field sample analysi
Xiao Yu (Shirley) Wu in the Leslie Dan Faculty of Pharmacy – Molecular dynamics modeling and screening of excipients for designing amorphous solid dispersion formulations of poorly–soluble drugs

Ontario Research Fund – Small Infrastructure Fund:

Celina Baines in the department of ecology & evolutionary biology in the Faculty of Arts & Science – Impacts of environmental change on organismal movement
Sergio de la Barrera in the department of physics in the Faculty of Arts & Science – Facility for quantum materials and device assembly from atomically thin van der Waals layers
Michelle Bendeck in the department of laboratory medicine & pathobiology in the Temerty Faculty of Medicine – 4D quantitative cardiovascular physiology centre
Laurent Bozec in the department of laboratory medicine & pathobiology in the Temerty Faculty of Medicine – 21st Century challenge for Dentistry: Breaking the cycle of irreversible dental tissue loss
Mark Chiew at Sunnybrook Health Sciences Centre and the department of medical biophysics in the Temerty Faculty of Medicine – Next generation computational MRI for rapid neuroimaging and image-guided therapy
Haissi Cui in the department of chemistry in the Faculty of Arts & Science – A molecule to mouse approach to study the intracellular localization of genetic code interpretation in mammalian cells
Andy Kin On DeVeale at the University Health Network and the Dalla Lana School of Public Health – Sarcopenia and musculoskeletal interactions (sami) collaborative hub
Ali Dolatabadi in the department of mechanical & industrial engineering in the Faculty of Applied Science & Engineering – Advanced cold spray facility
Spencer Freeman at the Hospital for Sick Children and the department of biochemistry in the Temerty Faculty of Medicine – Imaging biophysical determinants of the innate immune response
Liisa Galea at the Centre for Addiction and Mental Health and the Institute of Medical Science in the Temerty Faculty of Medicine – Sex and sex-specific factors influencing brain health across the lifespan
Maged Goubran at Sunnybrook Health Sciences Centre and the department of medical biophysics in the Temerty Faculty of Medicine – AI platform for mapping, tracking and predicting circuit alterations in Alzheimer’s disease
Eitan Grinspun in the departments of computer science and department of mathematics in the Faculty of Arts & Science – A computer graphics perspective on entanglement of slender structures
Levon Halabelian in the Department of Pharmacology and Toxicology in the Temerty Faculty of Medicine – Enabling a high-throughput drug discovery pipeline for targeting disease-related human proteins
Ziqing Hong in the department of physics in the Faculty of Arts & Science – Ultra-sensitive cryogenic detector development for dark matter and neutrino experiments
Eno Hysi at the Unity Health Toronto and the department of medical biophysics in the Temerty Faculty of Medicine – Structural and functional assessments of diabetic skin microvasculature using photoacoustic imaging
Lewis Kay in the department of biochemistry in the Temerty Faculty of Medicine – Helium recovery system for the biomolecular NMR facility
Xiang Li in the department of chemistry and the department of physic in the Faculty of Arts & Science – Real-time multi-faceted probes of quantum materials
Qian Lin in the department of cell & systems biology in the Faculty of Arts & Science – 2p-RAM for whole-brain single-neuron imaging of behaving zebrafish to study neural mechanisms of cognitive behaviours
Xilin Liu in the Edward S. Rogers Sr. department of electrical and computer engineering in the Faculty of Applied Science & Engineering – Integrated circuits for wireless brain implants with multi-modal neural interfaces
Stephen Lye at the Sinai Health System and the department of physiology in the Temerty Faculty of Medicine – Healthy Life Trajectories Initiative (HeLTI) analytics platform
Caitlin Maikawa in the Institute of Biomedical Engineering in the Faculty of Applied Science & Engineering – Biointerfacing materials for drug delivery lab
Emma Master in the department of chemical engineering & applied chemistry in the Faculty of Applied Science & Engineering – Accelerating biomanufacturing innovation through enhanced capacity for scale-up and downstream bioprocess engineering
Roman Melnyk at the Hospital for Sick Children and the department of biochemistry in the Temerty Faculty of Medicine – The H-SCREEN: A platform for high throughput and high content imaging-based small molecule screens for disease modulation
Juan Mena-Parra in the department of astronomy & astrophysics in the Faculty of Arts & Science – An advanced laboratory to enable novel radio telescopes for cosmology and time-domain astrophysics
Seyed Mohamad Moosavi in the department of chemical engineering and applied chemistry in the Faculty of Applied Science & Engineering – Machine learning for nanoporous materials design
Enid Montague in the department of mechanical & industrial engineering in the Faculty of Applied Science & Engineering – Automation and equity in healthcare laboratory
Michael Norris in the department of biochemistry in the Temerty Faculty of Medicine – Infrastructure for structural and functional virology research hub
Amaya Perez-Brumer in the Dalla Lana School of Public Health – 3P lab: Centering power, privilege and positionality for health equity research
Monica Ramsey in the department of anthropology at the �ؿ�ζSM Mississauga – Ramsey Laboratory for Environmental Archaeology (RLEA): How human-environment interactions shaped plant-food
Arneet Saltzman in the department of cell & systems biology in the in the Faculty of Arts & Science – Heterochromatin regulation in development and inheritance
Mina Tadrous in the Leslie Dan Faculty of Pharmacy – Developing a centre for real-world evidence to improve the use of medications for Canadians
Shurui Zhou in the department of electrical & computer engineering in the Faculty of Applied Science & Engineering – Improving collaboration efficiency for fork-based software development
Olena Zhulyn at the Hospital for Sick Children and the department of molecular genetics in the Temerty Faculty of Medicine – Targeting translation for tissue regeneration and repair
Christoph Zrenner at the Centre for Addiction and Mental Health and the Institute of Biomedical Engineering in the Faculty of Applied Science & Engineering – Next-generation real-time closed-loop personalized neurostimulation

Researchers' lab technique could speed forensic analysis in sexual assault cases

Christopher.Sorensen — Tue, 17 Sep 2024 14:43:28 +0000

Researchers' lab technique could speed forensic analysis in sexual assault cases

Christopher.Sorensen Tue, 09/17/2024 - 10:43

Cutline

(photo by Science Photo Library/Getty Images)

Chris Sasaki

Topic

Breaking Research

Centre for Research and Applications in Fluidic Technologies

Institute of Biomedical Engineering

Donnelly Centre for Cellular & Biomolecular Research

U of T Mississauga

A team of researchers has developed a new approach to analyzing DNA evidence in sexual assault cases – one that could reduce lengthy delays in the processing of evidence.

While there are almost half a million sexual assaults in Canada every year, many more go unreported because victims are reluctant to come forward.

One of the reasons cited by victims is that analysis of forensic evidence is too slow.

Mohamed Elsayed (supplied image)

“For this research, we read reports and surveys that asked victims why they weren’t reporting assaults,” says the study’s lead author Mohamed Elsayed, who worked on the project as part of his PhD in biomedical engineering at the �ؿ�ζSM. “And the most common answer was that they didn't have confidence in the justice system – and that lack of confidence was partly because of how long the process takes.”

Elsayed, now a post-doctoral researcher in the department of chemistry in the Faculty of Arts & Science, co-authored the study with, among others, Leticia Bodo, a master’s student in the department of chemistry, and Aaron Wheeler, a professor in the department of chemistry, the Institute of Biomedical Engineering and the Centre for Research and Applications in Fluidic Technologies, a U of T institutional strategic initiative.

All three researchers are also affiliated with the Donnelly Centre for Cellular and Biomolecular Research.

Processing forensic evidence in sexual assault cases is a technical, multi-step process that involves collecting DNA evidence and sending it to a well-equipped forensic laboratory for analysis by a skilled technician. Once there, the sample is first processed to isolate the assailant’s DNA from the victim’s so the assailant’s DNA can then be analyzed and used to identify a suspect.

The entire process can take days, weeks or longer. Most of that time is taken up with transporting the evidence to the lab, where its analysis can be further delayed depending on how many other cases are being investigated.

To speed things up, researchers focused on the first step: separating two individuals’ DNA from a single sample. At present, this is usually done manually by trained and experienced experts.

Elsayed and his collaborators, by contrast, developed a process called ’differential digestion” using digital microfluidics that helped simplify the overall process and reduce the number of manual steps needed to isolate the assailant’s DNA from 13 to five. “Also, because micro-fluidic processes tend to be faster, we expect that one of the eventual benefits will be shortening the overall time needed,” says Elsayed.

What’s more, the new approach could lead to a mobile solution that no longer requires a lab. For example, testing could be done at a hospital, circumventing the lab’s queue.

The new technique, described in a paper published in the journal Advanced Science, is compatible with the technology known as Rapid DNA analysis that is already in use for the second step of identifying an individual from their DNA. The study’s authors, which included researchers from U of T Mississauga’s forensic science program, say the long-term goal is to integrate the two technologies to make the process even more streamlined.

While there remain several challenges to deploying the new technique, Elsayed says he is confident they can be overcome and has turned his efforts toward making it widely accessible and commercially viable.

“Our plan is to develop an instrument that will do in five minutes what currently takes 45,” says Elsayed. “And to run many more samples than previously. Once we do that, the next step would be to introduce the technology to forensic labs and hospitals.

“It will take years, but the potential is very exciting.”

The research was supported by the ANDE Corporation and NSERC Alliance Society.

"I’m grateful to NSERC for having the foresight to establish the ‘Alliance Society’ program which has a mission to ‘address a societal challenge that will result in new natural sciences and engineering knowledge and societal impact,” Wheeler says.

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Forensic Science

U of T community members recognized with Order of Canada

bresgead — Thu, 04 Jul 2024 16:49:13 +0000

U of T community members recognized with Order of Canada

bresgead Thu, 07/04/2024 - 12:49

Cutline

(photo by Sgt Johanie Maheu, Rideau Hall, OSGG-BSGG)

Adina Bresge

Topic

Temerty Faculty of Medicine

Unity Health

Institute of Health Policy Management and Evaluation

Alumni

Dalla Lana School of Public Health

Hospital for Sick Children

Faculty of Music

Leslie Dan Faculty of Pharmacy

Order of Canada

Political Science

St. Michael's College

University College

University Health Network

Victoria College

Subheadline

"The Order of Canada recognizes individuals who have made positive and lasting impacts on communities here in Canada or who have brought honour to our country abroad"

An innovator in chemical catalyst development. A global leader in cardiac surgery and care. And a public health expert who led the rollout of Canada’s first colon cancer screening program.

These are a few members of the �ؿ�ζSM community who were recently honoured with appointments or promotions within the Order of Canada.

The Governor General recently announced 83 new appointments to the Order of Canada, including two promotions within the Order.

They include Doug Stephan, a University Professor of chemistry in the Faculty of Arts & Science; Lee Errett, a professor in the Temerty Faculty of Medicine’s department of surgery, and Linda Rabeneck, a health executive and professor in the Temerty Faculty of Medicine and the Dalla Lana School of Public Health.

Established in 1967, the Order of Canada is one of the country’s highest honours, recognizing extraordinary contributions across all sectors of society.

“The Order of Canada recognizes individuals who have made positive and lasting impacts on communities here in Canada or who have brought honour to our country abroad,” Gov. Gen. Mary Simon said in a statement.

Here is a list of U of T faculty, alumni and supporters who were appointed to, or promoted within, the Order of Canada in the latest round of honourees.

Current and former faculty

Edward Cole, a staff nephrologist at Toronto General Hospital and professor in the Temerty Faculty of Medicine’s department of medicine, was named a Member of the Order for his dedication to advancing and delivering care to people living with kidney disease, his instrumental role in establishing a globally impactful kidney-paired donation program and his leadership as former physician-in-chief at the University Health Network.

Lee Errett, a professor in the Temerty Faculty of Medicine’s department of surgery, was appointed a Member of the Order for his transformative leadership in cardiac research and care, including his role in establishing St. Michael’s Hospital as a world-class centre for cardiac surgery, his dedication to educating future medical leaders and providing care in underserved areas worldwide.

Franklyn Griffiths, a professor emeritus and George Ignatieff Chair Emeritus of Peace and Conflict Studies in the department of political science in the Faculty of Arts & Science, was appointed a Member of the Order for his scholarship on Russian affairs which has advanced the Western world’s understanding of Soviet politics. An expert in Arctic international relations, Griffiths helped create the Arctic Council and pushed for Indigenous voices to play a central role in the council’s workings.

Beverley Johnston, an internationally renowned percussionist who is an adjunct professor in the Faculty of Music, was appointed an Officer of the Order for her work developing and promoting Canadian music to audiences around the world. Working in a male-dominated field, Johnston’s unconventional performances combine classical transcriptions, contemporary music and an element of theatre.

Daphne Maurer, a professor emeritus of psychology, neuroscience and behaviour at McMaster University who holds a status appointment at U of T’s Institute of Health Policy Management and Evaluation in the Dalla Lana School of Public Health, was appointed an Officer of the Order for her research on visual and cognitive development in early childhood.

Linda Rabeneck, a gastroenterologist, health executive and professor in the Temerty Faculty of Medicine and the Dalla Lana School of Public Health, was named a Member of the Order for her leadership in colorectal cancer screening and prevention. Formerly the director of the Division of Gastroenterology at U of T, she led the rollout of ColonCancerCheck, Canada’s first province-wide screening program.

Stephen Randall, who earned his master's degree and doctorate at U of T and taught at the university from 1971 to 1974, was named a Member of the Order for his academic contributions and advisory role in international relations. A professor emeritus at the University of Calgary, Randall’s expertise in myriad issues affecting the United States and Latin America, notably Colombia, has informed Canada’s foreign policy.

Bibudhendra Sarkar, senior scientist emeritus at the Research Institute of the Hospital for Sick Children and professor emeritus at U of T’s department of biochemistry in the Temerty Faculty of Medicine, was named a Member of the Order for his achievements in advancing medical research in Canada and abroad. He discovered a novel treatment for patients with Menkes disease, a rare genetic condition, and led international efforts in South and Southeast Asia to address public health crises from contaminated groundwater.

Jonathan Scott Rose, a professor in the Edward S. Rogers Sr. department of electrical and computer engineering in the Faculty of Applied Science & Engineering, was named a Member of the Order for his pioneering work in architecture and software used in field-programmable gate arrays. Rose served as the chair of the department from 2004 to 2009 and received his PhD degree in electrical engineering from U of T in 1986.

Doug Stephan, a University Professor in the department of chemistry in the Faculty of Arts & Science, was named an Officer of the Order in recognition his world-leading research in inorganic and organometallic chemistry. His many achievements include discovering – and commercializing – a new class of catalysts that is now used in one of the largest chemical manufacturing facilities in the world. He also achieved global renown for founding the field of “Frustrated Lewis Pair” chemistry.

Alumni and friends

Sleight-of-hand artist David Ben, who graduated from University College in 1983, was named a Member of the Order for his four decades of dedication to the exploration, development and preservation of magic, including penning several books on the subject and co-founding the Magicana organization.

William Fox, a research fellow and adjunct professor at Trent University who earned his honours bachelor of arts and master of arts in archeology at U of T, was named a Member of the Order for his distinguished contributions to Canadian archeology, his leadership in the Ontario Archaeological Society, and his steadfast advocacy for the involvement of Indigenous communities in preserving their material heritage.

Martha Friendly, who founded the Childcare Resource and Research Unit at U of T’s Centre for Urban and Community Studies in the early 1980s, was appointed an Officer of the Order for her work with the now-independent non-profit and her advocacy for accessible, publicly funded early childhood education and care, and women’s equality.

Rosemary Ganley, a writer, activist, teacher and an alumna of St. Michael’s College, was named a Member of the Order for her lifelong advocacy for human rights, gender equity, and social justice, including co-founding Jamaican Self Help, an organization of Canadians working to support the development of healthy Jamaican communities.

Arnie Gelbart, a member of the Chancellors’ Circle of Benefactors, was named a Member of the Order for his decades-long leadership in independent film and television in his role as founder, executive producer and CEO of Galafilm Productions Inc.

Judy Kent was named a Member of the Order for championing sport as a catalyst for social change, her advocacy for gender equality and inclusion and her leadership in international support. Among her achievements: She was the first woman to serve as both president of Commonwealth Sport Canada and Canada’s chef de mission for the Commonwealth Games, and her paper on sport for international development laid the foundation for the SportWORKS program.

James David Meekison, with a 45-year career spanning investment banking, cable television and private equity, was named a Member of the Order for his extensive philanthropy. The Jim Meekison and Carolyn Keystone Foundation supported U of T’s Leslie Dan Faculty of Pharmacy’s efforts to launch the Discovery Pharmacy on the St. George campus.

Michael Perley, a U of T alumnus who completed a master’s degree in French language and literature, was named a Member of the Order for his lifelong dedication to tackling environmental and health challenges. He has been an advocate for tighter tobacco control laws, reducing second-hand smoke exposure and has led coalitions on acid rain and air pollution.

Dan Poenaru, a pediatric surgeon and professor at McGill University who earned two degrees at U of T, was named a Member of the Order for his contributions to pediatric surgery in Africa, including establishing a surgical unit and training program in Kenya, co-founding three medical schools and leading initiatives for children's surgery globally.

Vaira Vike-Freiberga, an alumna of Victoria College and the first woman to serve as Latvia’s president, was named an honorary Officer of the Order for her work enriching Canada-Latvia relations and for reflecting Canadian values abroad.

– with files from Mariam Matti and Rahul Kalvapalle

Canadian Hub for Health Intelligence and Innovation in Infectious Diseases awarded $72 million

Christopher.Sorensen — Mon, 06 May 2024 16:07:51 +0000

Canadian Hub for Health Intelligence and Innovation in Infectious Diseases awarded $72 million

Christopher.Sorensen Mon, 05/06/2024 - 12:07

Cutline

(photo by Nick Iwanyshyn)

Topic

Institutional Strategic Initiatives

Leah Cowen

PRiME

Sinai Health

Temerty Faculty of Medicine

Unity Health

Subheadline

Federal funding will be used to strengthen talent development and health intelligence in order to respond to emerging health threats

Four research programs in the Canadian Hub for Health Intelligence and Innovation in Infectious Diseases (HI³) have received $72 million in federal funding from the Canada Biomedical Research Fund (CBRF) and Biomedical Research Infrastructure Fund (BRIF), bolstering the country’s biomanufacturing capacity and readiness to respond to emerging health threats.

Support for HI³ and the four funded research programs through the CBRF and BRIF is part of a larger investment in Canada’s Biomanufacturing and Life Sciences Strategy. The strategy aims to grow a strong, competitive domestic life sciences sector with cutting-edge biomanufacturing capabilities and to improve the country’s ability to respond to future health challenges.

HI³ – a coalition of 87 academic, hospital, research networks, industry, government, not-for-profit and community partners – was one of five national hubs established in March 2023 with CBRF funding.

Together, the four awarded programs will provide critical health intelligence data to guide the co-development of health threat surveillance platforms and next-generation precision interventions by the hub’s academic and industry partners, while building a highly skilled workforce to support Canada’s growing biomanufacturing and life sciences sector.

“Congratulations to HI³ and the collaborative teams behind these CBRF-funded programs. These four programs leverage the tremendous expertise of the �ؿ�ζSM's researchers and our partners in academia, hospitals, industry and other sectors to develop the talent, tools and data required to be at the forefront of emerging health threats,” said Leah Cowen, U of T’s vice-president, research and innovation, and strategic initiatives.

“On behalf of the �ؿ�ζSM and HI³, I thank the government of Canada for its investment in building a strong domestic life sciences sector ready to take on the health challenges of today and tomorrow.”

One of the CBRF-funded programs is the Biomanufacturing Hub Network (BioHubNet), an immersive talent development program based at U of T and led by University Professor Molly Shoichet along with Darius Rackus, an assistant professor of chemistry and biology at Toronto Metropolitan University, and Gilbert Walker, a professor of chemistry at U of T.

“With world-leading scientists and researchers established across Canadian leading research institutions, Canada is home to a competitive and robust biomanufacturing and life sciences sector. We made a promise to Canadians that we would rebuild the domestic sector,” said François-Philippe Champagne, Canada’s minister of innovation, science and industry. “With this investment, our government is delivering on this promise by supporting the excellent innovations, collaborations and infrastructures necessary to rapidly respond to future public health threats and keep Canadians safe.”

The predicted supply of biomanufacturing workers is only enough to fill one-quarter of the positions that will be needed in the sector by 2029, according to a 2021 report from BioTalent Canada.

To address the shortage, BioHubNet will leverage its 26 industry and training partners – which include multinational and homegrown biotechnology companies, as well as five Ontario colleges and nearly $19 million in funding from CBRF – to develop a range of training programs and curricula that provide experiential, hands-on learning to graduate students, postdoctoral fellows and others who are ready to transition to industry.

The program will also outfit entrepreneurs with the skills and resources they need to commercialize their lab-based innovations, further strengthening the translational pipeline. Over the next four years, BioHubNet will produce close to 1,000 highly skilled workers through micro-credential courses, industry internships, academic exchange placements and entrepreneurial training.

A central tenet underlying all BioHubNet’s offerings is a commitment to create more equitable and inclusive participation in the biomanufacturing and life sciences sectors through intentional recruitment and active support for trainees from under-represented groups.

“Canada’s future as a leader in bio-innovation depends on having highly qualified workers, yet the sector is predicted to face severe workforce shortages in the coming years,” says Shoichet, who is the Michael E Charles Professor in Chemical Engineering at U of T and scientific director of PRiME Next-Generation Precision Medicine, a U of T institutional strategic initiative based at the Leslie Dan Faculty of Pharmacy.

“By expanding the pipeline of skilled research talent in Canada, BioHubNet will accelerate the translation of promising discoveries from bench to market and ensure that this country’s biomanufacturing sector continues to grow and attract further international investment.”

In addition to BioHubNet, three other research programs were also funded:

The Integrated Network for the Surveillance of Pathogens: Increasing Resilience and capacity in Canada’s pandemic response (INSPIRE) based at the University of Windsor. Co-led by Windsor professor Mike McKay and University of Guelph professor Lawrence Goodridge, the INSPIRE program leverages community-level wastewater surveillance data, infrastructure and expertise to monitor the arrival and spread of infectious threats. The program also received infrastructure funding from BRIF to implement technologies and processes across its network that will streamline wastewater surveillance efforts to be more rapid, agile and sensitive. Importantly, these infrastructure supports will expand wastewater monitoring capacity in northern Ontario and at the Windsor-Detroit border to strengthen supply chains.
The Prepare, React, Collect, Innovate, Share and Engage (PRECISE) Diagnostic Platform, based at Sinai Health and co-led by Jennie Johnstone and Anne-Claude Gingras – who are both faculty members in U of T’s Faculty of Medicine – will advance a comprehensive, streamlined approach for responding to emerging threats by driving the timely development of rapid diagnostic tools that will scale up testing capacity and reduce reliance on global supply chains.
The Pandemic Preparedness Engaging Primary Care and Emergency Departments (PREPARED) program, based at Unity Health Toronto and led by Andrew Pinto, who is a faculty member in the Temerty Faculty of Medicine, aims to engage primary care clinics and emergency departments across the country to enhance disease monitoring, improve patient care and health system efficiency, accelerate the development of medical countermeasures and boost recruitment to clinical trials.

All four research programs reflect the hub’s extensive network of nearly 100 partners from academia, hospital, industry, public and other sectors. The programs leverage the collective resources and expertise of this network, including U of T’s position as a global leader in artificial intelligence, data, life sciences and engineering, and the Toronto Academic Health Sciences Network’s strong track record of clinical impact and health-care innovation.

“Our goal at HI³ is to advance mission-driven, team-based science that will help Canada be more prepared, resilient and independent in the face of emerging health threats,” said Jen Gommerman, co-director of HI³ and a professor of immunology in U of T’s Temerty Faculty of Medicine.

“As we support and grow these four research programs, we will continue to work closely with our hub partners and with our counterparts across the country to ensure that we have the capacity and resources needed to respond in a co-ordinated, effective and equitable manner.”

U of T's Mark Lautens performs 100th citizenship ceremony

Christopher.Sorensen — Fri, 12 Apr 2024 14:28:40 +0000

U of T's Mark Lautens performs 100th citizenship ceremony

Christopher.Sorensen Fri, 04/12/2024 - 10:28

Cutline

University Professor Mark Lautens, chair of the department of chemistry, chose an event at the Mississauga Citizenship and Immigration Centre for his 100^th appearance as a presiding official (photo by Nick Iwanyshyn)

Alyx Dellamonica

Topic

Subheadline

University Professor and chair of the department of chemistry estimates he has sworn in as many as 6,000 new Canadians over the past decade

The �ؿ�ζSM’s Mark Lautens recently conducted his 100^thCanadian Citizenship Ceremony, officially welcoming 120 new Canadians from 31 countries of origin.

A University Professor and chair of the department of chemistry in the Faculty of Arts & Science, Lautens estimates that he may have sworn in as many as 6,000 new Canadians since 2014.

He chose an event held in the Mississauga Citizenship and Immigration Centre for his 100^th appearance as a presiding official. As is often the case, there were members of the university community at the ceremony, along with their families.

(photo by Nick Iwanyshyn)

“People are often excited to meet a scientist or a professor,” he says, adding that U of T alumni, students, faculty and staff whom he swears in often reach out afterward with their personal thanks and sometimes even ask if they can attend his classes.

“Officiants are encouraged to share some of their journey at the beginning of each ceremony and I talk about my mother, who came to Canada from the UK as a teenager, had a career as a legal secretary and then chose to complete high school after I became a professor.

“Many of the people at my ceremonies are especially touched by hearing that – both about my family and the transformative experience of pursuing higher education in Canada.”

(photo by Nick Iwanyshyn)

Lautens was first invited to preside in citizenship ceremonies after receiving the Order of Canada in 2014 for contributions at the forefront of organic chemistry. The honour qualifies Canadians to administer the Oath of Citizenship on a voluntary basis.

A passionate advocate for immigrants’ contributions to Canada, Lautens has written about the benefits for academic communities welcoming international students. "These individuals bring superb skills and a passion to succeed to their new home,” he wrote in a recent op-ed piece in the Globe and Mail.

(photo by Nick Iwanyshyn)

Even during the COVID-19 pandemic, Lautens says efforts were made to preserve a sense of occasion when the ceremonies became virtual affairs. Being unable to stand together with an officiant for a picture, for example, has evolved so that participants in remote ceremonies are urged to turn off their cameras at the end, leaving only the image of the presiding officer on the meeting screen. This allows everyone to take a selfie with the officiant – via the computer screen.

"I had to learn to hold a smile for a full minute,” Lautens says, “to ensure everyone has time to get a good picture.”

Acceleration Consortium funds $1.2 million worth of research projects powered by self-driving labs

Christopher.Sorensen — Wed, 06 Mar 2024 18:35:37 +0000

Acceleration Consortium funds $1.2 million worth of research projects powered by self-driving labs

Christopher.Sorensen Wed, 03/06/2024 - 13:35

Cutline

U of T Engineering researcher Yu Zou’s effort to develop improved materials for hip and knee replacements is among 12 projects receiving funding through the Acceleration Consortium (photo by Neil Ta)

Sean Bettam

Andrea Wiseman

Topic

Institutional Strategic Initiatives

Acceleration Consortium

Artificial Intelligence

Computer Science

U of T Scarborough

Subheadline

From joint replacements to sustainable chemical manufacturing, U of T projects aim to develop new materials that could yield scientific breakthroughs

Canada’s aging population is placing a host of new stressors on the health-care system, including an increasing number of hip and knee replacements that, in a best-case scenario, will last a maximum of 25 years using current materials.

With people living longer, that means there will be more subsequent surgeries to fix or replace the replacements — adding even more stress on the system.

New materials are needed to help solve this problem – and self-driving labs, or SDLs, can help. The labs combine artificial intelligence, robotics and advanced computing to discover new materials and molecules for commercial, clinical and industrial use in a fraction of the usual time and cost.

Yu Zou, an assistant professor in the department of materials science and engineering in the �ؿ�ζSM’s Faculty of Applied Science & Engineering, is using an SDL to rapidly test combinations of elements in his quest to develop alloys that can be used in longer-lasting joint replacements.

His work is just one example of the problems being tackled by scientists who have received a total of $1.2 million in Accelerate Grants through the Acceleration Consortium, a U of T institutional strategic initiative that is accelerating the discovery of new materials using SDL technologies.

The Acceleration Consortium is funding a diverse array of research efforts across nine departments in the Faculty of Applied Science & Engineering, the Faculty of Arts & Science, the Leslie Dan Faculty of Pharmacy and the �ؿ�ζSM Scarborough. Zou’s research is one of 12 new research projects that are either developing technologies that will support the development of SDLs or using SDL technologies to accelerate discovery.

Made possible by the $200 million grant from the Canada First Research Excellence Fund (CFREF) awarded to the Acceleration Consortium last April – the largest federal research grant ever awarded to a Canadian university – the projects enabled by the grant promise innovative advances in fields ranging from health care and climate change to sustainable materials design and food waste management.

“Using AI and automation to carry out more laboratory experiments in a smarter way, we’ve supercharged the process of scientific discovery,” said Alán Aspuru-Guzik¸ director of the Acceleration Consortium and professor in the departments of chemistry and computer science in the Faculty of Arts & Science. “These 12 Accelerate Grants are not only an investment in science, but are an investment in our future.

“The creativity and the diversity of thought shown by the researchers on these projects tells me that the materially different future that the Acceleration Consortium is striving for is achievable in our lifetime.”

The Acceleration Consortium awarded the 12 grants in three categories: Accelerate Seed, which builds accelerated discovery capacity at U of T by helping faculty members enter the field or collaborate with those already doing accelerated discovery; Accelerate Moonshot, which support high-risk, high-reward grants that will make significant contributions to the development or use of SDLs; and Accelerate Translation, which support accelerated discovery projects with clear commercialization goals and viable market potential, as well as the implementation or scaling of knowledge mobilization activities, training, and community engagement.

“This suite of Acceleration Grants is an excellent example of how the Acceleration Consortium is advancing the globally recognized strategic research mission of the �ؿ�ζSM in a way that’s critical for Canada to remain competitive on the international stage,” said Leah Cowen, U of T’s vice-president, research and innovation, and strategic initiatives. “By enabling the next generation of scientists to use self-driving labs and fostering research collaboration and partnerships between departments and institutions, these grants will enable the recipients to conduct high-impact, interdisciplinary accelerated research to discover materials that will improve our world.

“I congratulate the principal investigators and their teams who are leading these varied investigations, and I look forward to seeing their results in the accelerated timeline now made possible in part by CFREF and the remarkable demonstration of support for their work.”

While the CFREF funding will help to further advancements made by several researchers who are recognized as leaders in their fields, most support is going to early-career scientists who are pioneering new discoveries just as SDL technology is emerging as a revolutionary approach to knowledge.

Projects dedicated to the continuous improvement of SDL technology are also being funded. For example, a project by Nandita Vijaykumar, an assistant professor in the department of computer and mathematical sciences at U of T Scarborough, will develop software that can better manage the fast-flowing data streams SDLs create as well as the resources required to run the experiments.

“The work our grant recipients are doing will help us ensure that the Greater Toronto Area and Canada remain world leaders in AI-frontier discovery,” said Aspuru-Guzik. “And we’re doing so with innovative contributions from people at every stage of their career, with an eye to developing the next generation of groundbreaking researchers along the way. No one is resting on their laurels; each grant recipient and member of the AC is pushing the edge of what is possible and is working towards a materially better future.”

The Acceleration Consortium will welcome proposals for its next funding competition in summer 2024.

Read the story and full list of grant recipients at the Acceleration Consortium

Read the story and full list of grant recipients at the Faculty of Arts & Science

U of T researcher leads breakthrough in production of green carbon monoxide using light

Christopher.Sorensen — Mon, 11 Dec 2023 18:51:29 +0000

U of T researcher leads breakthrough in production of green carbon monoxide using light

Christopher.Sorensen Mon, 12/11/2023 - 13:51

Cutline

University Professor Geoffrey Ozin said the research aims to decarbonize the generation of industrial chemicals (supplied image)

Alyx Dellamonica

Topic

Breaking Research

Faculty of Arts & Science Staff

Sustainability

Subheadline

The process is an eco-friendly alternative to burning fossil fuels to generate industrial carbon monoxide

A team of advanced materials chemistry researchers, led by University Professor Geoffrey Ozin of the department of chemistry in the �ؿ�ζSM’s Faculty of Arts & Science, have made a significant breakthrough in the use of light to convert carbon and carbon dioxide (CO2) into carbon monoxide (CO).

In a study published in Energy and Environmental Science, Ozin and his team showcase the process, which represents an alternative to carbon-intensive methods of producing industrial carbon monoxide.

Carbon monoxide and carbon dioxide are both hazardous to human health, with rising carbon dioxide concentrations in our atmosphere increasing the threat of climate change induced by global warming. However, both gases are also vital elements of large-scale production of commodity chemicals and fuels.

In the chemical sector, for example, carbon monoxide serves as feedstock for the synthesis of acetic acid and methanol, pharmaceuticals, fragrance and polymers. In the food industry, it’s used for packaging of fresh meat products and to acidify carbonized beverages. Its uses are wide-ranging, from refining or removing rust from metals to serving as a key component of infrared lasers.

Creation of carbon monoxide for such applications is typically done via thermally powered processes involving the gasification of coal and partial oxidation of natural gas, processes that are associated with large carbon footprints and significant toxic byproducts.

Rather than burning fossil fuels to generate carbon monoxide, the greener approach being advanced by Ozin’s team utilizes light for the production process, combining this with the emerging practice of using carbon dioxide as chemical feedstock.

The source of carbon to enable this conversion process can be natural, the study shows. It may also come from fossil emission sources as well as air using specialized capture, storage and release technologies, or biochar made by slow burning of agricultural biomass.

The U of T team uses a light-powered reaction that employs this captured carbon dioxide, converting it to carbon monoxide in ways that are less energy- and chemical-intensive than the same reaction driven by heat.

“The CO generated photochemically by this means can justifiably be called green,” Ozin said.

A principal investigator in U of T’s interdisciplinary Solar Fuels Cluster, Ozin said the research group’s vision is to help gradually move the chemical and petrochemical industries away from their reliance on legacy fossil resources to more eco-friendly processes enabled by waste carbon dioxide and carbon, driven by light in solar refineries.

"By this means, it should prove feasible to decarbonize the generation of commodity chemicals and fuels, motivated by the desire to ameliorate greenhouse gas-induced climate change and global warming,” Ozin said.

Previous attempts at eco-friendly carbon monoxide production utilized thermal steam-gasification of fossil fuels, biomass or waste materials — super-heating the necessary feedstock with steam to produce the carbon monoxide. However, this generates a large carbon footprint and can be hampered by issues like ash melting and tar contamination. The process requires injections of pure oxygen and produces combustion-related contaminants like dioxins and furans.

Ozin’s team is instead spearheading photochemistry methods that can be carried out at room temperature, while generating fewer contaminants.

Green carbon monoxide generation is expected to become more economically viable as advancements are made in the efficiency of photoreactors, battery performance, solar concentration optics and light-emitting diodes – with improvements in these technologies vital to making it competitive with existing thermochemical and electrochemical production methods.

Ultimately, transitioning production of carbon monoxide away from processes that burn fossil fuels toward using renewable energy, unwanted atmospheric carbon monoxide and waste forms of carbon offers the prospect of reducing the environmental footprint of producing this toxic yet vital industrial chemical – while also helping to create green sector jobs.

U of T breaks ground on a new home for the Acceleration Consortium

Christopher.Sorensen — Wed, 15 Nov 2023 14:14:37 +0000

U of T breaks ground on a new home for the Acceleration Consortium

Christopher.Sorensen Wed, 11/15/2023 - 09:14

Cutline

A rendering of the Lash Miller building expansion (image courtesy of Mikkelsen Arkitekter AS / Cumulus Architects)

Topic

Institutional Strategic Initiatives

Acceleration Consortium

Artificial Intelligence

Subheadline

The expansion of the Lash Miller building also includes upgrades to department of chemistry labs, classrooms and other spaces

The �ؿ�ζSM recently held a groundbreaking ceremony to mark the expansion of the Lash Miller building on the St. George campus – a place that will serve as the new home of the Acceleration Consortium while providing improved facilities for the department of chemistry.

An institutional strategic initiative launched in 2021, the Acceleration Consortium fuses artificial intelligence, robotics, engineering and chemistry to accelerate the design and discovery of new materials.

Using self-driving laboratories powered by AI, the consortium works to discover materials needed to build a more sustainable, prosperous and healthy future.

“The research being done at the Acceleration Consortium is a cutting-edge approach to materials discovery,” said Melanie Woodin, dean of the Faculty of Arts & Science. “Now, more than ever, we need such new technologies to help solve the world's most existential and intractable problems, from climate change to plastics pollution to cancer.

“This expansion is truly about advancing the university’s mission of research and teaching excellence.”

From left to right: Mark Lautens, chair of the department of chemistry, Alán Aspuru-Guzik, director of the Acceleration Consortium, Anna Kennedy, chair of Governing Council, Melanie Woodin, dean of the Faculty of Arts & Science, and Robert Batey, former chair of the department of chemistry (photo by Diana Tyszko)

The university earlier this year received a grant of $200 million from the Canada First Research Excellence Fund (CFREF) – the largest federal research grant ever awarded to a Canadian university – to support the Acceleration Consortium’s research.

“Developing such innovative technologies is made possible by the federal government's visionary investment. This grant allows us to do big science, ensuring Canada remains competitive on the international stage,” said Woodin.

The building expansion will also include renovations to the department of chemistry, with upgrades being made to labs, classrooms and faculty and administrative space to provide students and scientists with enhanced facilities for research, learning and innovation.

“I've watched the plans emerge from both the department and the Faculty side, and it's really an amazing project,” said Mark Lautens, chair of the department of chemistry. “The self-driving labs are the cornerstone of the AC, but there will be new lecture theatres and some amazing meeting spaces for chemistry that will figure very prominently in the design.

“Our students will be prepared for the future, regardless of how that future unfolds.”

Robert Batey, former chair of the department of chemistry, also reflected on the origins of the project, the founding of the Acceleration Consortium and the initial success in enlisting Alán Aspuru-Guzik, director of the consortium, to lead U of T’s efforts in the emerging field of machine learning-guided materials development.

Faculty, staff and members of the design and construction teams gathered for a recent groundbreaking event (photo by Diana Tyszko)

“This project really has been a long time in gestation. In 2017, we saw an opportunity to take advantage of a nascent and emerging field of science and technology, which is AI and machine learning, and how it might be applied to, and enabled by, chemistry and automation,” Batey said.

The revolutionary work being done at the Acceleration Consortium will be key in positioning Canada as a world leader in materials discovery, with a state-of-the-art space that will not only house this important work, but also attract top tier talent.

“The AC building represents a new global era where countries are looking inward while at the same time collaborating with each other,” said Aspuru-Guzik. “We're building a team of people who are going to be able to take advantage of this new space and of the federal grant to move the needle and make Canada the leader in materials discovery.”

A rendering of the interior of the Lash Miller building’s expansion (Image courtesy of Mikkelsen Arkitekter AS / Cumulus Architects)

The Acceleration Consortium considers and includes contributions from several other disciplines of study in its work.

“We are very excited that this project is also integrated with Canadian society in such areas as Indigenous scholarship, social sciences and economics,” said Aspuru-Guzik. “Materials discovery has to do with everything, and impacts society in a very complex way.”

Anna Kennedy, chair of U of T’s Governing Council, acknowledged the impact the consortium has already made at the university.

“Since its launch, and under the expert guidance of Alán and other brilliant scholars, the AC has solidified itself as one of the university’s most impressive institutional strategic initiatives and as the embodiment of the �ؿ�ζSM’s capacity to support large-scale, high-impact interdisciplinary research.”

Woodin also noted the importance of philanthropy in leveraging the historic support from the federal government and investment by industry partners.

“Inspired giving by donors will enable us to build a contemporary space that will attract talent that's needed to advance the goals of the Acceleration Consortium, which will have major economic benefits for the Greater Toronto Area and for Canada,” she said.

The Lash Miller building expansion is set to be completed in the spring of 2026. The complex project is being delivered through an integrated design team led by the university’s Planning, Design & Construction (UPDC) portfolio and a collaboration between Canadian firm Cumulus Architects and Danish firm Mikkelsen Architects, among other firms specializing in key areas of the project design and technical specifications.

The construction will be completed by Urbacon.

Global experts gather at U of T to discuss how ‘self driving labs’ will revolutionize scientific discovery

Christopher.Sorensen — Thu, 31 Aug 2023 18:44:06 +0000

Global experts gather at U of T to discuss how ‘self driving labs’ will revolutionize scientific discovery

Christopher.Sorensen Thu, 08/31/2023 - 14:44

Cutline

Linda Hung, manager of Toyota Research Institute, speaks at this year’s Accelerate Conference at U of T (photo by Worker Bee Supply © Acceleration Consortium)

Catrina Kronfli

Topic

Acceleration Consortium

Artificial Intelligence

Computer Science

Creative Destruction Lab

Leslie Dan Faculty of Pharmacy

History

Rotman School of Management

Subheadline

The Acceleration Consortium’s second-annual Accelerate conference focused on talent development, collaboration and commercialization

The Acceleration Consortium (AC) at the �ؿ�ζSM recently brought together more than 350 representatives from academia, industry and government from 16 countries to discuss how “self-driving labs” are revolutionizing the speed and impact of scientific discovery.

Held over four days in August, the consortium’s second annual Accelerate conference focused on key themes such as talent development, collaboration and commercialization – all with an eye to finding and developing new materials and molecules that can help solve humanity’s most pressing challenges, from climate change to pandemics.

Alán Aspuru-Guzik, director of the AC and a professor in U of T’s departments of chemistry and computer science in the Faculty of Arts & Science, said the conference has quickly emerged as a major draw in a field that’s rapidly gaining momentum around the world.

“The Acceleration Consortium’s Accelerate Conference attracts the world’s leading academic and industry researchers working to accelerate scientific discovery,” he said. “Given the tremendous growth and excitement we have seen since launching the conference just one year ago, it is clear Accelerate is becoming the flagship event for accelerated discovery.”

A U of T Institutional Strategic Initiative that launched in 2021, the AC earlier this year received a $200-million grant from the Canada First Research Excellence Fund (CFREF) to help it achieve its bold vision of realizing the age of materials on demand.

The largest federal research grant ever awarded to a Canadian university, the CFREF grant allows the consortium to bring together researchers and industry to design, develop and implement self-driving lab technologies. These labs combine the power of artificial intelligence (AI) with robotics and advanced computing to create new materials and molecules needed for a sustainable future – at a fraction of the usual time and cost. Applications include everything from life-saving medications to biodegradable plastics.

Chandra Veer Singh, an associate professor in the department of materials science and engineering in the Faculty of Applied Science & Engineering, and Christine Allen, a professor at the Leslie Dan Faculty of Pharmacy, noted AI will be critical to a variety of careers in the future and that continuous learning is necessary to equip workers with the knowledge and skills needed to fill these roles.

Sterling Baird, the AC’s director of training and programs, spoke about the consortium’s upcoming digital discovery program – the first of its kind in Canada. Thanks to support from the Ontario Micro-credentials Fund, the program will train scientists looking to apply AI to materials discovery. Flora Wan, a technical education specialist with the Vector Institute, shared the programs that the institute developed to help professionals and businesses develop AI knowledge.

As an emerging field, ecosystem development is also important. Anjuli Szawiola, policy analyst with Natural Resources Canada, spoke to the two networks the federal government is co-leading – Materials for Energy and the German-Canadian Materials Acceleration Centre – to promote knowledge sharing and the adoption of advanced materials for clean energy in Canada and abroad.

For its part, the AC has become a magnet for cross-sector collaboration as its partners look to gain access to the wide range of expertise, research and innovation it has assembled.

The consortium includes more than 100 academics from more than 40 research institutes and 30 private and public sector organizations. Together, they are creating a global community to tackle key challenges in the field such as data sharing and reproducibility of self-driving labs.

Michelle Murphy, a professor in the department of history in U of T’s Faculty of Arts & Science and a Canada Research Chair in Science & Technology Studies and Environmental Data Justice, spoke about the importance of incorporating social scientists and Indigenous communities in the research process given the ethical implications of speeding up the pace of science.

Murphy will examine critical issues associated with self-driving labs, including ensuring that those impacted most by the technology have a say in its development in order to prevent unintended harms, whether direct or indirect. With this in mind, equity, diversity and inclusion will continue to guide the AC’s project implementation and research design.

On the topic of commercialization, Sonia Sennik, executive director of the Creative Destruction Lab (CDL), shared the non-profit’s history of and philosophy towards supporting entrepreneurs.

“New founders have thousands of things on their to-do list. CDL believes the best judgment an early-stage entrepreneur can get is ‘entrepreneurial judgement’ from an experienced entrepreneur,” Sennik explained. CDL’s program allows select entrepreneurs to benefit from the entrepreneurial knowledge of fellows and associates who help guide CDL ventures.

Co-founded by Aspuru-Guzik, CDL’s Matter Stream is working with the AC to help founders seeking to discover, develop or recycle materials.

What comes next? The AC will assemble a steering committee to tackle various issues facing the sector. In addition to building six self-driving labs and a machine learning and automation lab, the consortium is hiring new scientists, chemists, AI experts, roboticists and more, with the goal of making the Greater Toronto Area and Canada a world leader in accelerated materials discovery.

With files from Erin Warner and Tabassum Siddiqui

New photoreactor technology could pave the way to a carbon-neutral future, researchers say

siddiq22 — Wed, 09 Aug 2023 17:00:32 +0000

New photoreactor technology could pave the way to a carbon-neutral future, researchers say

siddiq22 Wed, 08/09/2023 - 13:00

Cutline

(Photo courtesy of Karlsruhe Institute of Technology)

Topic